Assessment of chemicals
Focus
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Occupational biomonitoring
Occupational Biomonitoring allows to measure internal exposure or effect. It is especially efficient in assessing exposures from multiple routes, i.e. inhalation, oral and dermal exposure pathways. This project is focused on improving methods for deriving health based human biomarker values (BMGV, BLV, DNELbiomarker). Such biomarker values can be used to interpret measured levels of biomarkers in a risk assessment context.
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Webinar: Gaining acceptance in next generation PBK modelling approaches for regulatory assessments
10 May 2021 @ 13:20 - 15:30 (CEST) | The OECD is increasingly exploring the use of alternative (non-animal) methods to aid the chemical risk assessment process. Recently, the OECD published a Guidance Document on the Characterisation, Validation and Reporting of Physiologically Based Kinetic (PBK) Models for Regulatory Purposes. This guidance aims to increase the confidence in the use of PBK models parameterised with data derived from in vitro and in silico methods, and help address “unfamiliar” uncertainties associated with these methods.
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Quantitative Structure-Activity Relationships Project [QSARs]
Quantitative Structure-Activity Relationships [(Q)SARs] are methods for estimating properties of a chemical from its molecular structure and have the potential to provide information on hazards of chemicals, while reducing time needed to generate data, monetary cost and animal testing currently needed.
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OECD assists countries in developing and harmonising methods for assessing risk to human health and the environment, including methodologies for hazard and exposure assessment.
KEY AREAS OF WORK
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OECD works with member countries and other stakeholders to cooperatively assess the hazards of industrial chemicals to generate OECD-agreed assessments that are available to the public and that can be used for priority setting, risk assessment and other activities within national or regional programmes. |
Risks of chemicals on human health and the environment are assessed by combining the chemical-specific hazard data and the estimation of the extent to which man and other organisms are exposed to chemicals. OECD has been working mainly on environmental exposure assessment for more than 10 years. |
User Tools
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eChemPortal is an Internet gateway to information on the properties, hazards & risks of chemicals found in the environment, homes and workplaces, and in everyday products. |
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The Toolbox is a software application to identify and fill (eco)toxicological data gaps for chemicals hazard assessment. Grouping chemicals into chemical categories is crucual to the workflow.
This environmental toolkit gives access to practical tools on environmental risk assessment and mgt of chemicals, by linking to relevant OECD products that can be used in each step of the work flow.|
International Uniform ChemicaL Information Database (IUCLID) 6
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Product Release and Exposure Data Warehouse
The Warehouse is a database designed to house existing data on releases of chemicals from, and exposures to, commercial and consumer end products. |
The OECD Harmonised Templates are standard data formats for reporting studies done on chemicals to determine their properties or effects on human health and the environment. 
ENGAGE WITH US
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